Giant Multiloculated Ameloblastoma Causing Extensive Destruction of the Mandible and Midface: A Case Report

Hamza Benghaleb *

Otorhinolaryngology and Head and Neck Surgery Department, IBN ROCHD University Hospital, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco.

Salma Bensimimou

Otorhinolaryngology and Head and Neck Surgery Department, IBN ROCHD University Hospital, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco.

Meriem Lahjaouej

Otorhinolaryngology and Head and Neck Surgery Department, IBN ROCHD University Hospital, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco.

Myriam Loudghiri

Otorhinolaryngology and Head and Neck Surgery Department, IBN ROCHD University Hospital, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco.

Walid Bijou

Otorhinolaryngology and Head and Neck Surgery Department, IBN ROCHD University Hospital, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco.

Youssef Oukessou

Otorhinolaryngology and Head and Neck Surgery Department, IBN ROCHD University Hospital, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco.

Sami Rouadi

Otorhinolaryngology and Head and Neck Surgery Department, IBN ROCHD University Hospital, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco.

Redallah Abada

Otorhinolaryngology and Head and Neck Surgery Department, IBN ROCHD University Hospital, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco.

Mohamed Roubal

Otorhinolaryngology and Head and Neck Surgery Department, IBN ROCHD University Hospital, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco.

Mohamed Mahtar

Otorhinolaryngology and Head and Neck Surgery Department, IBN ROCHD University Hospital, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco.

*Author to whom correspondence should be addressed.


Abstract

Ameloblastoma is a slow-growing odontogenic tumor that can cause painless swelling of the face. The local aggressive behavior of the tumor may directly damage surrounding soft and hard tissues. The study aims to report a rare case of a giant multiloculated ameloblastoma with extensive mandibular and midfacial destruction and to highlight its diagnostic and surgical management challenges. Herein we present a rare case of giant ameloblastoma in a male patient with massive enlargement of the left side of the face, resorption of hemi-mandible and left maxilla, and destruction of facial skeleton. Treatment consisted of radical hemimandibulectomy for removal of the tumorous mass, with stabilization using a reconstruction plate. For giant ameloblastoma, the diagnosis and treatment strategies for each surgical intervention depend on an accurate understanding of anatomical structures, including their positions and spatial relationships. CT imaging facilitates precise identification of the lesion's extent and location, providing additional critical information that can assist in the selection of suitable treatment options. In summary, despite the stability of human anatomy over time, accurate understanding of anatomical structures and their clinical manifestations remains essential for effective diagnosis and formulation of treatment strategies in contemporary surgical practices.

Keywords: Ameloblastoma, facial, hemi mandibulectomy, mandible, facial swelling


How to Cite

Benghaleb, Hamza, Salma Bensimimou, Meriem Lahjaouej, Myriam Loudghiri, Walid Bijou, Youssef Oukessou, Sami Rouadi, Redallah Abada, Mohamed Roubal, and Mohamed Mahtar. 2025. “Giant Multiloculated Ameloblastoma Causing Extensive Destruction of the Mandible and Midface: A Case Report”. Asian Journal of Case Reports in Surgery 8 (2):852-58. https://doi.org/10.9734/ajcrs/2025/v8i2729.

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