Asian Journal of Case Reports in Surgery

Extra-Gastrointestinal Stromal Tumors (EGISTs) : A Case Report and Review of Literature

S. N. Jatal *

Jatal Hospital and Research Centre, Latur, India.

Sudhir Jatal

Jatal Hospital and Research Centre, Latur, India and Tata Hospital, Mumbai, India.

Ajay Punpale

MIMSR Medical College, Latur, India.

Sachin Ingle

MIMSR Medical College, Latur, India.

*Author to whom correspondence should be addressed.

---

Abstract

Gastrointestinal stromal tumor (GIST) represent less than 1% of all gastro intestinal stromal tumors (GISTS) and are main in the stomach and small intestine. Mesenteric GIST is rarely reported as they constitute 5 to 10% of GIST. It originates from the intestinal cells of Cajal. GISTS that develops outside the gastrointestinal tract and have no connection with the intestinal wall or serosal surface of the gastrointestinal tubular organs.

An extra-intestinal gastrointestinal stromal tumors (EGITS) they have similar morphological and immune-histological characteristics as GISTS. Surgical resection is the main stay of treatment. Post-operative use to imatinib, delay the recurrence and improves to survival rate.

We report a rare case of mesenteric extra-gastrointestinal stromal tumor (EGITS) in a 50 years old female and discuss the course of clinical presentation, diagnosis and  management.

Keywords: Gastrointestinal stromal tumor, mesenteric GIST, surgical resection, imatinib

---

---

---

References

Gregorio Arellano-Gutiérrez, Edwin Leopoldo Maldonado-García,Primary extra-gastrointestinal stromal tumor (EGIST) of the mesentery: Case report and review of literature, Annals of Medicine and Surgery; 2018.

Available:https://doi.org/10.1016/j.amsu.2020.11.020

Rajalakshmi R, Rajakumar V. A case of mesenteric gastro intestinal stromal tumors: a diagnostic dilemma. International Surgery Journal. 2022;9. 2076. DOI:10.18203/2349-2902.isj20223176

AK Das, Tarjina Begum, Bedanta Barman , Prajna Anirvan, Mesenteric GIST: A case report, The Journal of Medical Research Research (medicinearticle.com) 2018;4(1):4-6.

Abood HBA, Albalawi AND, AlEnazi HO, Almuhanna MM, Busaad NO, Jarad RG. Alkhamis A, Alsharif MS, Alahdal SM, Alqahtani MAS, Alhakamy DAS, AR. Alraqibah SA. Overview on Gastrointestinal Stromal Tumor; A Review, Journal of Pharmaceutical Research International. 2021;33(56B):29–36. Doi: 10.9734/jpri/2021/v33i56B33925

Bhadani PP, Singh A., Gupta GK, Parasar K. An unusual appearance of cystic gastro intestinal stromal tumor of small intestine - A case report and brief review of literature. Journal of Advances in Medicine and Medical Research. 2022;34(20):282 -88. Available:https://doi.org/10.9734/jammr/2022/v34i2031496.

Caterino S, Lorenzon L, Petrucciani N, Iannicelli E, Pilozzi E, Romiti A, Ziparo, V. Gastrointestinal stromal tumors: Correlation between symptoms at presentation, tumor location and prognostic factors in 47 consecutive patients. World Journal of Surgical Oncology. 2011;9:1-10.

Abidoye O, Johnson A Extremely Aggressive Mesenteric Extra gastrointestinal Stromal Tumor: A Case Report and Literature Review. Cureus 2022;14(3):e23108. DOI:10.7759/cureus.23108

Ramani AS, Huske G, Noronha FP. A Rare Case of Mesenteric Gastrointestinal Stromal Tumor Presenting as Acute Abdomen. Niger J Surg. 2017;23(1): 71-72. DOI: 10.4103/1117-6806.199960. PMID: 28584517; PMCID: PMC5441222.

Feng, F, Feng, B, Liu, S, Liu, Z, Xu, G, Guo, M, Lian, X, Fan, D, & Zhang, H. Clinicopathological features and prognosis of mesenteric gastrointestinal stromal tumor: evaluation of a pooled case series. Oncotarget 2017 Jul 11;8(28):46514-46522

Gupta, N., Mittal, S., Lal, N. et al. A rare case of primary mesenteric gastrointestinal stromal tumor with metastasis to the cervix uteri. World J Surg Onc. 2007;5: 137. Available:https://doi.org/10.1186/1477-7819-5-137

Tiwari, A. , Choudhary, A. , Khowal, H. , Chaudhary, P. and Arora, M. (2013) Primary Extra-Gastrointestinal Stromal Tumor (GIST) arising from mesentery of small bowel and presenting as abdominal mass: A rare entity. Open Journal of Gastroenterology. 2013;3:267-271. DOI: 10.4236/ojgas.2013.35045.

Gaillard F, Niknejad M, Knipe H, et al. Gastrointestinal stromal tumor. Reference article, Radiopaedia.org

Available:https://doi.org/10.53347/rID-6758

(Accessed on 30 May 2024).

Engin G, Asoglu O, Kapran Y. et al. A gastrointestinal stromal tumor with mesenteric and retroperitoneal invasion. World J Surg Onc. 2007;5:121. Availble:https://doi.org/10.1186/1477-7819-5-121