Giant Ovarian Tumor: A Case Report and Review of the Literature
Amine Maazouz *
Department of Visceral Surgery 1, Faculty of Medicine and Pharmacy, Mohammed V Military Hospital, Rabat, Morocco.
Yosra Asatach
Department of Visceral Surgery 1, Faculty of Medicine and Pharmacy, Mohammed V Military Hospital, Rabat, Morocco.
Mohammed Lamghari
Department of Visceral Surgery 1, Faculty of Medicine and Pharmacy, Mohammed V Military Hospital, Rabat, Morocco.
Maroua Sabur Kadhem
Department of Visceral Surgery 1, Faculty of Medicine and Pharmacy, Mohammed V Military Hospital, Rabat, Morocco.
Imad El-Azzaoui
Department of Visceral Surgery 1, Faculty of Medicine and Pharmacy, Mohammed V Military Hospital, Rabat, Morocco.
Hind Habladje
Department of Visceral Surgery 1, Faculty of Medicine and Pharmacy, Mohammed V Military Hospital, Rabat, Morocco.
Mohammed Najih
Department of Visceral Surgery 1, Faculty of Medicine and Pharmacy, Mohammed V Military Hospital, Rabat, Morocco.
Hakim El-Kaoui
Department of Visceral Surgery 1, Faculty of Medicine and Pharmacy, Mohammed V Military Hospital, Rabat, Morocco.
Sidi Mohamed Bouchentouf
Department of Visceral Surgery 1, Faculty of Medicine and Pharmacy, Mohammed V Military Hospital, Rabat, Morocco.
Ahmed Bounaim
Department of Visceral Surgery 1, Faculty of Medicine and Pharmacy, Mohammed V Military Hospital, Rabat, Morocco.
Mountassir Moujahid
Department of Visceral Surgery 1, Faculty of Medicine and Pharmacy, Mohammed V Military Hospital, Rabat, Morocco.
*Author to whom correspondence should be addressed.
Abstract
Epithelial ovarian cancer is the most lethal gynecological cancer. Serous-type epithelial ovarian cancer, the most common form with more than 50% of cases, is often diagnosed late and associated with a poor prognosis.
This is a retrospective study on a patient who was diagnosed with a clinically benign giant ovarian tumor and who was hospitalized in the visceral surgery department "I" at the Mohamed V Military Instruction Hospital in Rabat.
The surgical intervention allowed complete excision of the mass (R0 resection). Likewise, we performed a hysterectomy, bilateral adnexectomy, omentectomy and appendectomy without lymph node dissection.
Histological examination was compatible with a morphological appearance and an immunohistochemical profile in favor of a high-grade serous ovarian carcinoma.
Adjuvant chemotherapy type treatment based on PACLITAXEL 280 CARBOPLATINE 650 spread over 6 cycles.
The evolution was favorable in our patient, with a follow-up of one year without any sign of recurrence.
Keywords: Ovary, ovarian giant mass, Serous carcinoma
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References
Ovarian tumors – National College of Gynecologists and Obstetricians French (CNGOF). Date of creation of the 2010-2011 document.
Lansac J, Marret H. Tumors of the ovary- Gynecology – For the practitioner-Elsevier Masson SAS-All rights reserved.
Item 303: Ovarian Cancer -CODEX. revision 14/12/2020. Available:S-ECN.COM.
Sajous C, Péron J, Bakrin N, Bolze P-A, Glehen O, Kepenekian V, et al. Medical treatment of epithelial ovarian cancers- P. Corbaux. EMC – Gynecology - Elsevier Masson SAS. All Rights reserved - ©; 2021.
Grouthier V, Leban M, Bachelot A. Methods of exploration of ovarian function. EMC – Endocrinology-Nutrition – Elsevier Masson SAS. All rights reserved.
Ovarian tumors – French College of Pathologists (CoPath)–. Francophone Virtual Medical University; 2013.
Brun JL, Boubli B, Sasco AJ. Epidemiology of ovarian tumors- EMC - Gynecology - Elsevier Masson SAS. All rights reserved-©; 2012.
Cancer Registry of the National Institute of Oncology. Rabat, Morocco; 2008.
Malignant neoplasm, malignant disease of lymphatic tissue or hematopoietic ovarian cancer-Doctor’s guides and lists of acts and services (LAP) drawn up in collaboration with the High Authority of Health (HAS) and the National Cancer Institute (INCa); 2010.
Herbst AL. The epidemiology of ovarian carcinoma and the current status of tumor markers to detect disease. Am J Obstet Gynecol. 1994;170(4):1099-105; discussion 1105. DOI: 10.1016/s0002-9378(94)70104-0, PMID 8166193.
Characterization of new pre-chemotherapy and post-chemotherapy cell lines for epithelial ovarian cancer - Thesis presented at the Faculty of Medicine with a view to obtaining the Master's degree (M.Sc.) in molecular biology - by LuLin Wang - University of Montreal Faculty of medicine; 2011.
The female genitalia – DR. Seddiki. Bougrassa.D – Service of Histology-Embryology. Faculty of Medicine, University of Oran-2019; 2020.
Ovarian cancer ovarian carcinoma, Cancer leagues in Switzerland: proximity, individual support, confidentiality and professionalism – Berne 3e revised and corrected edition. 2011;2008.
Ovarian cancer or the murderer who whispers in women’s ears-Geneviève Ostiguy – practical guide to gyneco – oncology for the clinician – le Médecin du Québec. 2006;41.
Rare malignant tumors of the ovarian management diagnostic and therapeutic – Update 2016/2017 has been carried out by the Multidisciplinary Consultation Unit in Oncology gynecology’ of the university plateau of Caen and by the Unit of Multidisciplinary consultation in ’Gynecological Oncology’ of the plateau University of Rouen. Regional Cancer Network; 2017.
Surgical strategies in borderline ovarian tumors -p. Morice, E. Bentivegna, A. Maulard, Miailhe G, Devouassoux-Shisheboran M, Genestie C, Gouy S, Elsevier Masson SAS. All rights reserved. EMC - Surgical techniques - Gynecology - ©; 2018.
Bentivegna E, Gouy S, Maulard A, Miailhe G, Morice P, Elsevier Masson SAS. Surgery for malignant epithelial tumors of the ovary- All rights reserved -EMC – Surgical techniques – Gynecology.
Talerman A, Vang R. Germ cell tumors of the ovary. In: Kurman RJ, Ellenson LH, Ronnett BM, editors. Blaustein’s pathology of the female genital tract. New York: Springer. 2011;847-908.
Griffiths CT, Parker LM, Fuller AF. Role of cytoreductive surgical treatment in the management of advanced ovarian cancer. Cancer Treat Rep. 1979;63(2):235-40. PMID 445502.
Chi DS, Eisenhauer EL, Lang J, Huh J, Haddad L, Abu-Rustum NR, et al. What is the optimal goal of primary cytoreductive surgery for bulky stage IIIC epithelial ovarian carcinoma (EOC)? Gynecol Oncol. 2006;103(2):559-64.
DOI: 10.1016/j.ygyno.2006.03.051, PMID 16714056.
Pignata S, Scambia G, Katsaros D, Gallo C, Pujade-Lauraine E, De Placido S, et al. Carboplatin plus paclitaxel once a week versus every 3 weeks in patients with advanced ovarian cancer (MITO-7): a randomised, multicenter, open-label, phase 3 trial. Lancet Oncol. 2014;15(4): 396-405. DOI: 10.1016/S1470-2045(14)70049-X, PMID 24582486.
Dion L, Mairé M, Brousse S, Joste M, Nyangoh Timoh K, Foucher F, Sardain H, Henno S, Levêque J, Lavoué V. Ovarian cancer: genetics, diagnosis, assessment, therapeutic strateg. EMC - Gynecology – Elsevier Masson SAS. All rights reserved - ©; 2021.