Asian Journal of Case Reports in Surgery

Introduction: Angiomyofibroblastoma is a rare condition that presents as a painless slowly progressing scrotal mass, and it can be misdiagnosed as a testicular tumor. Among para-testicular tumors, the most common benign tumors are lipomas, adenomatoid tumors and leiomyomas. The rarest benign tumor presented in this region is angiomyofibroblastoma. Among the para-testicular tumours, the angiomyofibroblastoma is rarer and in male individuals it is still rare.

Presentation: Presenting concern was a 40-year gentleman presenting with painless scrotal mass for 1½ year with normal tumor markers. Ultrasonography, a large intrascrotal cavity mass was revealed. Exploration of the scrotum and high inguinal orchidectomy was done after proper consent. Histopathology and immuno-histo-chemistry of this extratesticular mass revealed angiomyofibroblastoma with CD 34+ DESMIN++++ ER++ S 100--

Discussion: Only less than 25 such cases have been reported earlier all over the world. Among the tumors occurring in the scrotum, angiomyofibroblastoma-like tumors are benign mesenchymal formations. Genital AMFB’s (Angiomyofibroblastoma) has partially myxoid proliferation that demonstrated considerable variation in cellular density, but it also possesses two integral components: blood vessels and stromal cells. All AMFB’s (Angiomyofibroblastoma) showed immunoreactivity for vimentin, desmin, actin and estrogen receptor protein.

Conclusion: The purpose of the current study is to be increased the knowledge regarding a very rare paratesticular tumor, angiomyofibroblastoma, keeping it as a differential diagnosis for scrotal tumors. The detailed study of this rare benign tumour helps to add to the previous such case reports and helps in making of specific management protocols so as the treatment of such tumours will become easier to the future cases.